ITT Pure-Flo Bio-Pure fractional manual bonnet.
Bio-Pure is a compact manual diaphragm-valve platform for fractional, low-flow high-purity service. Its manual bonnet is used on Bio-Pure bodies for sampling, bioreactors, chromatography systems, filtration skids, and portable vessels, with top-entry maintenance and a common compressor connection for compatible PTFE and elastomer diaphragms.
What ITT Pure-Flo Bio-Pure fractional manual bonnet is—and where it fits.
Bio-Pure is a compact manual diaphragm-valve platform for fractional, low-flow high-purity service. Its manual bonnet is used on Bio-Pure bodies for sampling, bioreactors, chromatography systems, filtration skids, and portable vessels, with top-entry maintenance and a common compressor connection for compatible PTFE and elastomer diaphragms.
Where it fits
Use Bio-Pure where compact fractional flow control and a wide body/end-connection choice are needed. Confirm exact body size, end connection, diaphragm, pressure, temperature, SIP/CIP/COP protocol, and BPM versus sealed/clean-out options.
What to confirm
Confirm the compatible valve body and size, diaphragm and compressor connection, pressure and temperature, washdown or autoclave conditions, sealed-bonnet or travel-stop options, and operator access.
How Triplex helps
Triplex helps keep the actuator conversation tied to the complete valve package so the hardware works in the plant, not just on a datasheet.
What Triplex will want to know.
Good valve recommendations come from process context. A few details up front prevent a lot of expensive back-and-forth later.
| Selection point | Why it matters | Triplex note |
|---|---|---|
| Manual or automated operation | Manual bonnets, pneumatic actuators, and stainless actuator options solve different plant realities. | Confirm who operates the valve and how often it cycles. |
| Fail position and force | Actuator sizing depends on valve size, diaphragm, process pressure, and fail-open/fail-closed expectations. | Do not size the actuator from the actuator name alone. |
| Controls and environment | Feedback, solenoids, washdown exposure, and service access can determine the best topworks package. | Triplex can help coordinate actuator, switch package, and documentation needs. |
Manufacturer literature and related Triplex resources.
Use these documents as a starting point, then confirm final selection against the actual process conditions.
Keep the selection connected to the full ITT valve platform.
Actuation overview
Compare this item against related ITT options before narrowing the valve package.
PlatformPure-Flo diaphragm valves
Review the full Pure-Flo platform around body, diaphragm, bonnet, actuator, and controls decisions.
PlatformEnviZion platform
Use the EnviZion family page when the valve package belongs in that platform conversation.
Need help applying Bio-Pure Manual Bonnet?
Send the valve size, connection style, product, process conditions, cleaning/sterilization method, actuation preference, controls needs, and any documentation requirements.
Talk to Triplex
