ITT Pure-Flo integral chromatography valve.
The CHRO and CHN chromatography bodies integrate four or five diaphragm valves into one machined assembly. They route flow forward through the chromatography column, reverse through the column, and—with CHRO—around the column, replacing a larger five-valve piping arrangement while reducing dead legs, hold-up, contact area, and skid space.
What ITT Pure-Flo integral chromatography valve is—and where it fits.
The CHRO and CHN chromatography bodies integrate four or five diaphragm valves into one machined assembly. They route flow forward through the chromatography column, reverse through the column, and—with CHRO—around the column, replacing a larger five-valve piping arrangement while reducing dead legs, hold-up, contact area, and skid space.
Where it fits
Use it at chromatography-column inlet and outlet stations where compact, cleanable bidirectional routing is required. Confirm CHRO with bypass versus CHN without bypass, column connections, flow direction, valve sequence, drainability, actuator layout, and automation logic.
What to confirm
Valve size, end connections, orientation, drain angle, material, surface finish, diaphragm material, actuator or bonnet style, and documentation expectations should all be checked before quoting.
How Triplex helps
Triplex helps translate the process problem into a practical ITT body selection so the valve package fits the line, the cleaning method, and the maintenance plan.
What Triplex will want to know.
Good valve recommendations come from process context. A few details up front prevent a lot of expensive back-and-forth later.
| Selection point | Why it matters | Triplex note |
|---|---|---|
| Process purpose | Shutoff, sample, purge, drain, divert, tank outlet, or aseptic barrier duty changes the correct body geometry. | Start with what the valve has to do in the process, not just the valve size. |
| Cleanability and hold-up | Dead legs, drainability, and internal volume can matter as much as pressure and temperature. | Send sketches or photos when the valve location is part of a skid or vessel connection. |
| Topworks and diaphragm | The body decision should be made with bonnet/actuator and diaphragm material in mind. | Triplex can help pair the body with manual or pneumatic operation and the right diaphragm review. |
Manufacturer literature and related Triplex resources.
Use these documents as a starting point, then confirm final selection against the actual process conditions.
Keep the selection connected to the full ITT valve platform.
Valve body overview
Compare this item against related ITT options before narrowing the valve package.
PlatformPure-Flo diaphragm valves
Review the full Pure-Flo platform around body, diaphragm, bonnet, actuator, and controls decisions.
PlatformEnviZion platform
Use the EnviZion family page when the valve package belongs in that platform conversation.
Need help applying Chromatography?
Send the valve size, connection style, product, process conditions, cleaning/sterilization method, actuation preference, controls needs, and any documentation requirements.
Talk to Triplex
